Gentamicin

An excellent aminoglycoside antibiotic drug, Gentamicin is prescribed to treat bacterial infections, especially that which is caused by Gram-negative bacteria. Gentamicin Sulfate Injection or USP comes as a sterile, nonpyrogenic solution of Gentamicin sulfate in water that is used for injection. Gentamicin dose is directed for intramuscular or intravenous route. This drug is highly effective when used in combination with a penicillin-type drug for the curing of endocarditis that is caused by group D streptococci.

Gentamicin Sulfate Injection is also highly effective in treating serious staphylococcal infections. Hypersensitivity towards the use of Gentamicin is a contraindication that is reported regarding the drug. Therefore, pregnant woman should avoid using this drug as it can affect reproduction capacity and even cause potential hazards to the fetus. Avoid premixing Gentamicin sulfate with other drugs. It should be administered separately according to the recommended route of administration and schedule of dosage. Bacterial resistance to Gentamicin is normally developed gradually.
Gentomicin toxicity or Gentomicin side effects include Nephrotoxicity or serious renal problems that include gentamicin ophthalmic problems or gentamicin eye problems along with vertigo, dizziness, tinnitus, roaring in the ears, hearing loss etc. Other unfavorable reactions associated with Gentamicin include lethargy, respiratory depression, visual disturbances, depression, confusion, weight loss, decreased appetite, hypotension, hypertension along with some possible side effects including itching, skin rash, urticaria, laryngeal edema, vomiting, localized burning, anaphylactoid reactions, fever, headache, increased salivation, nausea, joint pain, pseudotumor cerebri, stomatitis; purpura, acute organic brain syndrome, alopecia, pulmonary fibrosis, transient hepatomegaly, splenomegaly etc. Since the drug contains sodium metabisulfite, it can produce allergic reactions such as anaphylactic symptoms along with serious or asthmatic occurrence in certain people.
Gentamicin dosing is available in the form of gentamicin eye drops or gentamicin oilment. It is also available as gentamicin solution such as gentamicin reagent solution, gentamicin sulphate solution etc.